Commentary on our article

Marty Burke and his team from the University of Illinois at Urbana-Champaign have written a nice commentary in PNAS on our recent article there. Check it out from this reference:

 

PNAS 2017 114 (22) 5564-5566; published ahead of print May 22, 2017, doi:10.1073/pnas.1706266114

  • Wed
    Jun
    07
    2017

    Commentary on our article

    Marty Burke and his team from the University of Illinois at Urbana-Champaign have written a nice commentary in PNAS on our recent article there. Check it out from this reference:   PNAS 2017 114 (22) 5564-5566; published ahead of print May 22, 2017, doi:10.1073/pnas.1706266114
  • Thu
    May
    25
    2017

    The Speedvac is fixed

    Nobody outside our lab will care about this news article, but it really matters to our team! After a heroic struggle, the Speedvac is fixed.        Kenji and Cat tried... Joe tried....   even the Boss tried! Finally it is back in action. Now back to work!  
  • Fri
    May
    19
    2017

    Article featured in C&EN

    Our latest article has been featured in C&EN. Check it out here: http://cen.acs.org/articles/95/i20/Natural-product-analysis-offers-insight.html  
  • Mon
    May
    01
    2017

    Latest paper published in PNAS

    Our latest work describing our meta-analysis of all previously published NP structures from the microbial and marine worlds, has been published this afternoon. The work, which is a collaborative project with colleagues at UCSD and UCSC, describes our efforts to examine rates of novel natural product discovery over time, and the value of examining different source organisms for novel compound discovery.
  • Thu
    Mar
    02
    2017

    New article published with Payne group

    The latest results from our ongoing collaboration with the Payne group at the University of Sydney were published today in Nature Communications. Congratulations to the Payne group and everyone involved for the successful completion of a fascinating study.
  • Wed
    Mar
    01
    2017

    Jake wins poster competition

    Congratulations to Jake, who is one of the winners for the 2017 SFU Department of Chemistry poster competition. This award provides financial support to help Jake attend the 2017 ASP conference in Portland.
  • Fri
    Feb
    10
    2017

    Latest article with the Auerbuch lab published

    Our latest collaborative paper with the Auerbuch-Stone lab at UCSC has been published in mSphere. Congratulations to all involved!
  • Thu
    Aug
    11
    2016

    Postdoctoral position opened

    The Linington lab is looking for talented enthusiastic candidates for a new postdoctoral position at the interface of natural products and integrated Omics. Interested parties are encouraged to check out the flyer on the Opportunities page for more details.
  • Thu
    Aug
    11
    2016

    Linington lab recruiting grad students

    We have openings for several graduate student positions. Take a look at the Opportunities page for more details!
  • Wed
    Aug
    10
    2016

    GNPS Paper published

    The GNPS paper describing the development of a new open access platform for MS2 fingerprinting of natural products is published today in Nature Biotechnology. Led by Pieter Dorrestein and Nuno Banderia from UCSD, this project involved both our current postdoc Kenji Kurita, and one of our former graduate students, Laura Sanchez. Congratulations to all for a beautiful piece of work.
  • Sun
    May
    22
    2016

    Linington Lab features in Science

    The lab has been featured among a number of groups interested in cytological profiling in a news article in this week's edition of Science. Those with a subscription can read the original article here: http://science.sciencemag.org/content/352/6288/877
  • Sun
    May
    22
    2016

    Total synthesis of teixobactin published

    Jessie's collaboration with the Payne group from the University of Sydney in Australia has just been published in Organic Letters. Jessie provided screening data to support their report of the first total synthesis of the much lauded new natural product antibiotic teixobactin. Well done to all.
  • Sat
    Oct
    31
    2015

    Compound Activity Mapping covered in High Content Review

    The Compound Activity Mapping paper has been covered online by High Content Review. Check it out here.
  • Thu
    Oct
    01
    2015

    Spliceosome inhibitor paper published in JBC

    Bob and Bailey's collaboration with Kerstin Effenberger from Melissa Jurica's lab looking for natural product inhibitors of splicing has just been published in JBC. Congratulations to all on an interesting and exciting collaborative effort.
  • Thu
    Oct
    01
    2015

    Kenji and Emerson's paper in PNAS

    Kenji and Emerson's key paper on the development of Compound Activity Mapping appeared this week in PNAS. Congratulations to them both on an outstanding piece of work.
  • Fri
    Aug
    21
    2015

    Jessie's paper out today

    Jessie's first manuscript, describing the use of cytological profiling to explore our natural products library for compounds with specific phenotypes, is out today as an ASAP article in JNP. Congratulations to Jessie!
  • Sun
    Aug
    16
    2015

    Linington lab at SFU featured by Vice Media

    The Linington Lab has been featured in a new article on marine biotechnology. Check it out here: http://motherboard.vice.com/read/drugs-from-the-sea
  • Wed
    Jul
    01
    2015

    Linington Lab moves to Simon Fraser University

    Professor Linington and the Linington Lab have moved after eight wonderful years at the University of California Santa Cruz to take up a new position as a Canada Research Chair in High-Throughput Screening and Chemical Biology in the Department of Chemistry at Simon Fraser University. Please come and visit us if you are in the Vancouver area, and see our new labs, equipment and colleagues.
  • Thu
    Apr
    16
    2015

    Nature Reviews Microbiology article published

    Our joint review with the Yildiz lab has just been published in Nature Reviews Microbiology. Congratulations to the Yildiz team, and to our own Chris Warner who contributed to the project.
  • Thu
    Apr
    16
    2015

    Linington lab featured on Discovery Digital

    Our lab has recently been highlighted by the Discovery channel on their online site. You can check out this new segment, featuring our interest in antibiotic discovery, on our Movies page.
  • Mon
    Mar
    02
    2015

    Suffness review published in JNP

    Kenji and Roger's review of high-content strategies for natural products discovery, based on the Suffness award lecture, was published today in the Journal of Natural Products.
  • Thu
    Feb
    19
    2015

    Mail from the President

    Every year since he arrived in office we have included President Obama on our lab Christmas card list. This year he replied!!!!! Check out our card from President and First Lady Obama below.  
  • Wed
    Jan
    14
    2015

    Salinipostin manuscript out as a feature article in JOC

    Our first collaborative project with the Derisi lab at UCSF focused on antimalarial drug discovery has just been published in the Journal of Organic Chemistry. Congratulations to joint lead authors Chris, Gabe and Danny Ebert.
  • Tue
    Jan
    06
    2015

    Brian and Gabe's collaboration with Gilead published

    Congratulations to Brian, Gabe, Bailey and Monica, whose collaborative publication with Gilead Sciences has just been published in Organic Letters.
  • Sat
    Dec
    06
    2014

    Chris Warner's biofilm development paper published in ChemComm

    Chris Warner's paper describing the medicinal chemistry optimization and biological characterization of one of our biofilm inhibitors was published online today in ChemComm. Congratulations to Chris.
  • Sun
    Nov
    16
    2014

    Chris's borrelidin paper out today

    Chris's latest paper, describing a new borrelidin analogue discovered as part of his partnership with Pfizer and the Mankin lab at UIC, is out today in JNP. Congratulations to Chris and the team.
  • Wed
    Sep
    17
    2014

    New manuscript with the Fischbach lab

    Chris Schulze's collaboration with Mohamed Donia and Michael Fischbach describing a systematic evaluation of the biosynthetic capacity of bacteria from the human microbiome has just been published in Cell. Congratulations to all!
  • Mon
    Jul
    21
    2014

    Kenji's collaboration with the Fischbach lab published in Cell

    This manuscript describes the use of Clusterfinder (a new computational method for the unbiased discovery of natural product biosynthetic gene clusters (BGCs) from genomic data) to characterize global biosynthetic capacity of the bacterial and archeal kingdoms. Kenji's contribution focused on the isolation and identification of the product of a pair of widely distributed but previously uncharacterized BGCs. Congratulations to Kenji and the Fischbach team for the publication of a landmark paper!
  • Fri
    Jul
    04
    2014

    Kenji wins Piatt Scholarship

    Congratulations to Kenji who has been awarded a 2014 Piatt Fellowship from the Capitola-Aptos Rotary Club to support the final year of his dissertation work.
  • Fri
    Jul
    04
    2014

    Plus ça change....

    Five years have passed, and all the faces in this photo are different but one. Looks like global warming has improved the weather in Santa Cruz too.    Click here for enlarged version
  • Wed
    Jun
    11
    2014

    Dr. Linington wins Suffness award

    Dr. Linington has been selected as the American Society of Pharmacognosy 2014 Matt Suffness Young Investigator award winner. As part of this award he will be presenting the Suffness award lecture at the upcoming ASP annual meeting in Oxford, Mississippi in July 2014.
  • Tue
    Jun
    03
    2014

    Welcome to our newest postdoc Henrik from Germany

    Our newest postdoc, Dr. Henrik Harms,  has arrived this week from the laboratory of Prof. Gabriele König at the University of Bonn in Germany.
  • Tue
    Jun
    03
    2014

    Sloth project featured on the radio

    Our collaborator Dr. Sarah Higginbotham, who was the lead researcher on the sloth fur microbiome study, has been featured on the radio on the CBC show 'Quirks and Quarks'. You can listen to her interview here: http://www.cbc.ca/quirks/2014/05/31/2014-05-31-4/
  • Fri
    May
    16
    2014

    Brian wins dissertation year fellowship

    Congratulations to Brian, who has been awarded a campus dissertation year fellowship to support the final year of his PhD program.
  • Thu
    Apr
    24
    2014

    Jessie wins Douglas Wren award

    Jessie has won a Douglas Wren award for 2014, which recognizes academic achievement for senior graduate students, and will be awarded at the Bunnett Lecture next month. Congratulations to Jessie!
  • Tue
    Jan
    21
    2014

    Sloth fur as a source of novel microbial diversity

    Our latest paper, which was a contribution to a project led by Dr. Sarah Higginbotham from the Smithsonian Tropical Research Institute in Panama, describes her work on the discovery of novel fungal diversity from sloth fur, and the profiles of some of the extracts from this collection in our BioMAP screening assay system. This is part of the Panama ICBG program, which our lab has been part of for the last 7 years. Check it out here.
  • Tue
    Jan
    21
    2014

    Two for one in Antimicrobial Agents and Chemotherapy

    We have two separate articles coming out in the February issue of Antimicrobial Agents and Chemotherapy- one with our collaborator Vicki Auerbuch Stone on the discovery of novel type III secretion system inhibitors, and one with Prof. Fitnat Yildiz, also from the METOX department at UCSC, focused on the development of an image-based screen for finding novel inhibitors of biofilm formation in Pseudomonas aeruginosa.
  • Tue
    Dec
    10
    2013

    New article in the Journal of Antibiotics

    Weng has published another paper with collaborators from the Dorrestein lab that presents the use of BioMAP screening to profile antibiotics found using molecular networks.
  • Sun
    Dec
    01
    2013

    Chris has graduated with his Ph.D.

    Congratulations to Chris Schulze who is the latest graduate from our laboratory. We wish him well with his postdoc in Stanford.
  • Mon
    Nov
    18
    2013

    Welcome to our new visiting scientist from Brazil

    Joao Baldim has joined us for a year from Brazil to work on natural products discovery and target identification projects.
  • Wed
    Nov
    06
    2013

    New biofilm inhibitor publication

    Kelly has published her latest paper describing a new class of biofilm inhibitors with activity against both Vibrio cholerae and Pseudomonas aeruginosa.
  • Mon
    Aug
    26
    2013

    Gabe Navarro defends his thesis

    Congratulations to Gabe, who has defended his thesis, and is heading to a postdoc on the East coast
  • Mon
    Jun
    03
    2013

    New postdoc joins the group

    Welcome to Bob James, who has joined us from Dale Boger's lab at TSRI as a postdoc on the global health project