2023
| 109. | Mullowney, M. W.; Duncan, K. R.; Elsayed, S. S.; Garg, N.; van der Hooft, J. J. J.; Martin, N. I.; Meijer, D.; Terlouw, B. R.; Biermann, F.; Blin, K.; Durairaj, J.; Gorostiola González, M.; Helfrich, E. J. N.; Huber, F.; Leopold-Messer, S.; Rajan, K.; de Rond, T.; van Santen, J. A.; Sorokina, M.; Balunas, M. J.; Beniddir, M. A.; van Bergeijk, D. A.; Carroll, L. M.; Clark, C. M.; Clevert, D. A.; Dejong, C. A.; Du, C.; Ferrinho, S.; Grisoni, F.; Hofstetter, A.; Jespers, W.; Kalinina, O. V.; Kautsar, S. A.; Kim, H.; Leao, T. F.; Masschelein, J.; Rees, E. R.; Reher. R.; Reker, D.; Schwaller, P.; Segler, M.; Skinnider, M. A.; Walker, A. S.; Willighagen, E. L.; Zdrazil, B.; Ziemert, N.; Goss, R. J. M.; Guyomard, P.; Volkamer, A.; Gerwick, W. H.; Kim, H. U.; Müller, R.; van Wezel, G. P.; van Westen, G. J. P.*; Hirsch, A. K. H.*; Linington, R. G.*; Robinson, S. L.*; Medema, M. H.*"Artificial intelligence for natural product drug discovery.", Nature Reviews Drug Discovery, 2023, ASAP. doi: 10.1038/s41573-023-00774-7. |
| 108. | Recchia, M. J. J.; Baumeister, T. U. H.; Liu, D. Y.; Linington, R. G.* "MultiplexMS: A Mass Spectrometry-Based Multiplexing Strategy for Ultra-High-Throughput Analysis of Complex Mixtures", Analytical Chemistry, 2023, ASAP. doi: 10.1021/acs.analchem.3c00939. |
| 107. | Morehouse, N. J.; Flewelling, A. J.; Liu, D. Y.; Cavanagh, H.; Linington, R. G.; Johnson, J. A.; Gray, C. A.* "Tolypocaibols: Antibacterial Lipopeptaibols from a Tolypocladium sp. Endophyte of the Marine Macroalga Spongomorpha arcta", Journal of Natural Products, 2023, ASAP. doi: 10.1021/acs.jnatprod.3c00233. |
| 106. | Lin, F.; Kennelly, E. J.; Linington, R. G.*; Long, C.* "Comprehensive Metabolite Profiling of Two Edible Garcinia Species Based on UPLC-ESI-QTOF-MSE Coupled with Bioactivity Assays", Journal of Agricultural and Food Chemistry, 2023, 71, 7604–7617. doi: 10.1021/acs.jafc.2c08372. |
| 105. | Vidar, W. S.; Baumeister, T. U. H.; Caesar, L. K.; Kellogg, J. J.; Todd, D. A.; Linington, R. G.; Kvalheim, O. M.; Cech, N. B.* "Interaction Metabolomics to Discover Synergists in Natural Product Mixtures", Journal of Natural Products, 2023, 86, 655–671. doi: 10.1021/acs.jnatprod.2c00518. |
| 104. | Khadilkar, A.; Bunch, Z. L.; Wagoner, J.; Ravindran, V.; Oda, J. M.; Vidar, W. S.; Clark, T. N.; Manwill, P. K.; Todd, D. A.; Barr, S. A.; Olinger, L. K.; Fink, S. L.; Strangman, W. K.; Linington, R. G.; MacMillan, J. B.; Cech, N. B.; Polyak, S. J.* "Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents", Journal of Natural Products, 2023, 86, 1061–1073. doi: 10.1021/acs.jnatprod.3c00159. |
| 103. | Liu, D. Y.; Phillips, L.; Wilson, D. M.; Fulton, K. M.; Twine, S. M.; Wong, A.; Linington, R. G.* "Collateral Sensitivity Profiling in Drug-Resistant Escherichia coli Identifies Natural Products Suppressing Cephalosporin Resistance", Nature Communications, 2023, 14, 1976. doi: 10.1038/s41467-023-37624-4. |
| 102. | Morehouse, N. J.; Clark, T. N.; McMann, E. J. ;van Santen, J. A.; Haeckl, F. P. J.; Gray, C. A.; Linington, R. G.* "Annotation of Natural Product Compound Families Using Molecular Networking Topology and Structural Similarity Fingerprinting", Nature Communications, 2023, 14, 308. doi: 10.1038/s41467-022-35734-z. |
| 101. | Terlouw, B. R.; Blin, K.; Navarro-Muñoz, J. C.; Avalon, N. E.; Chevrette, M. G.; Egbert, S.; Lee, S.; Meijer, D.; Recchia, M. J. J.; Reitz, Z. L.; van Santen, J. A.; Selem-Mojica, N.; Tørring, T.; Zaroubi, L.; Alanjary, M.; Aleti, G.; Aguilar, C.; Al-Salihi, S. A. A.; Augustijn, H. E.; Avelar-Rivas, J. A.; Avitia-Domínguez, L. A.; Barona-Gómez, F.; Bernaldo-Agüero, J.; Bielinski, V. A.; Biermann, F.; Booth, T. J.; Carrion Bravo, V. J.; Castelo-Branco, R.; Chagas, F. O.; Cruz-Morales, P.; Du, C.; Duncan, K. R.; Gavriilidou, A.; Gayrard, D.; Gutiérrez-García, K.; Haslinger, K.; Helfrich, E. J. N.; van der Hooft, J. J. J.; Jati, A. P.; Kalkreuter, E.; Kalyvas, N.; Kang, K. B.; Kautsar, K.; Kim, W.; Kunjapur, A. M.; Li, Y.-X.; Lin, G.-M.; Loureiro, C.; Louwen, J. J. R.; Louwen, N. L. L.; Lund, G.; Parra, J.; Philmus, B.; Pourmohsenin, B.; Pronk, L. J. U.; Rego, A.; Rex, D. A. B.; Robinson, S.; Rosas-Becerra, L. R.; Roxborough, E. T.; Schorn, M. A.; Scobie, D. J.; Singh, K. S.; Sokolova, N.; Tang, X.; Udwary, D.; Vigneshwari, A.; Vind, K.; Vromans, S. P. J. M.; Waschulin, V.; Williams, S. E.; Winter, J. M.; Witte, T. E.; Xie, H.; Yang, D.; Yu, J.; Zdouc, M.; Zhong, Z.; Collemare, J.; Linington, R. G.; Weber, T.*; Medema, M. H.* "MIBiG 3.0: a community-driven effort to annotate experimentally validated biosynthetic gene clusters", Nucleic Acids Research, 2023, 51, D603-D610. doi: 10.1093/nar/gkac1049. |
2022
| 100. | Takaki, M.; Williams, D. E.; Freire, V. F.; Sartori, S. B.; Lira, S. P.; Bizarria Jr., R.; Rodrigues, A.; Gonçalves da Costa, D. R.; Amorim, M. R.; Ferreira, A. G.; Andersen, R. J.; Linington, R. G.*; Berlinck, R. G. S.* "Metabolomics Reveals a 26-Membered Macrolactone Produced by Endophytic Colletotrichum spp. from Alcatrazes Island, Brazil", Organic Letters, 2022, 24, 9381–9385. doi: 10.1021/acs.orglett.2c03531. |
| 99. | Hight, S. K.‡; Clark, T. N.‡; Kurita, K. L.; McMillan, E. A.; Bray, W.; Shaikh, A. F.; Khadilkar, A.; Haeckl, F. P. J.; Carnevale-Neto, F.; La, S. Lohith, A.; Vadena, R. M.; Lee, J.; Wei, S.; Lokey, R. S.; White, M. A.*; Linington, R. G.*; MacMillan, J. B.* "High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling", Proceedings of the National Academy of Sciences, USA, 2022, 119, e2208458119. doi: 10.1073/pnas.2208458119. |
| 98. | Houshmand, A.; Heroux, D.; Liu, D. Y.; Zhou, W.; Linington, R. G.; Bally, M.; Warren, J. J.; Walsby, C. J.* "Ferrocene-Appended Anthraquinone and Coumarin as Redox-Active Cytotoxins", Dalton Trans., 2022, 51, 11437-11447. doi: 10.1039/d2dt01251k. |
| 97. | Linington, R. G.*; Keller, L.; Choi, H.; Bertin, M. J. "Special Issue in Honor of Professor William Gerwick", Journal of Natural Products, 2022, 85, 459-461. doi: 10.1021/acs.jnatprod.2c00100. |
| 96. | Hawkins, P. M. E.; Hoi, D. M.; Cheung, C. Y.; Wang, T.; Quan, D.; Sasi, V. M.; Liu, D. Y.; Linington, R. G.; Jackson, C. J.; Oehlers, S. H.; Cook, G. M.; Britton, W. J.; Clausen, T.; Payne, R. J.* "Potent Bactericidal Antimycobacterials Targeting the Chaperone ClpC1 Based on the Depsipeptide Natural Products Ecumicin and Ohmyungsamycin A.", Journal of Medicinal Chemistry, 2022, 65, 4893–4908. doi: 10.1021/acs.jmedchem.1c02122. |
| 95. | Carnevale Neto, F.‡; Clark, T. N.‡; Lopes, N. P.; Linington, R. G.* "Evaluation of Ion Mobility Spectrometry for Improving Constitutional Assignment in Natural Product Mixtures", Journal of Natural Products, 2022, 85, 519-529. doi: 10.1021/acs.jnatprod.1c01048. |
| 94. | Lee, S.; van Santen, J. A.; Farzaneh, N.; Liu, D. Y.; Pye, C. R.; Baumeister, T. U. H.; Wong, W.-R.; Linington, R. G.* "NP Analyst: An Open Online Platform for Compound Activity Mapping", ACS Central Science, 2022, 8, 223-234. doi: 10.1021/acscentsci.1c01108. |
| 93. | Flores-Bocanegra, L.; Al Subeh, Z. Y.; Egan, J. M.; El-Elimat, T.; Raja, H. A.; Burdette, J. E.; Pearce, C. J.; Linington, R. G.*; Oberlies, N. H.* "Dereplication of Fungal Metabolites by NMR-Based Compound Networking Using MADByTE", The Journal of Natural Products, 2022, 85, 614-624. doi: 10.1021/acs.jnatprod.1c00841. |
| 92. | McCaughey , C.S.; van Santen, J. A.; van der Hooft, J. J. J.; Medema, M. H.; Linington, R. G.* "An Isotopic Labeling Approach Linking Natural Products with Biosynthetic Gene Clusters.", Nature Chemical Biology, 2022, 18, 295–304. doi: 10.1038/s41589-021-00949-6. |
| 91. | Wishart, D. S.*; Sayeeda, Z.; Budinski, Z.; Guo, A.; Lee, B.L.; Berjanskii, M.; Rout, M.; Peters, H.; Dizon, R.; Mah, R.; Torres-Calzada, C.; Hiebert-Giesbrecht, M.; Varshavi, D.; Varshavi, D.; Oler, E.; Allen, D.; Cao, X.; Gautam, V.; Maras, A.; Poynton, E. F.; Tavangar, P.; Yang, V.; van Santen, J. A.; Ghosh, R.; Sarma, S.; Knutson, E.; Sullivan, V.; Jystad, A. M.; Renslow, R.; Sumner, L. W.; Linington, R. G.; Cort, J. R. "NP-MRD: the Natural Products Magnetic Resonance Database", Nucleic Acids Research, 2022, 50, D665–D677. doi: 10.1093/nar/gkab1052. |
| 90. | van Santen, J. A.; Poynton, E. F.; Iskakova, D.; McMann, E.; Alsup, T. A.; Clark, T. N.; Fergusson, C. H.; Fewer, D. P.; Hughes, A. H.; McCadden, C. A.; Parra Villalobos, J.; Soldatou, S.; Rudolf, J. D.; Janssen, E. M.-L.; Duncan, K. R.; Linington, R. G.* "The Natural Products Atlas 2.0: A Database of Microbially-Derived Natural Products", Nucleic Acids Research, 2022, 50, D1317–D1323. doi: 10.1093/nar/gkab941. |
2021
| 89. | Tran, W.; Kusay, A. S.; Hawkins, P. M. E.; Cheung, C.-Y.; Nagalingam, G.; Pujari, V.; Ford, D. J.; Stoye, A.; Ochoa, J. L.; Audette,R. E.; Hortle, E.; Oehlers, S. H.; Charman, S. A.; Linington, R. G.; Rubin, E. J.; Dowson, C. G.; Roper, D. I.; Crick, D. C.; Balle, T.; Cook, G. M.; Britton, W. J.; Payne, R. J.* "Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors", The Journal of Medicinal Chemistry, 2021, 64, 17326–17345. doi: 10.1021/acs.jmedchem.1c01407. |
| 88. | Hawkins, P. M. E.; Liu, D. Y.; Linington, R. G.; Payne, R. J.* "Solid-phase synthesis of coralmycin A/ epi-coralmycin A and desmethoxycoralmycin A", Organic and Biomolecular Chemistry, 2021, 19, 6291-6300. doi: 10.1039/d1ob01062j. |
| 87. | Challa, V. R.; Kwon, D.; Taron, D.; Fan,H.; Kang, B.; Wilson, D.; Haeckl, F. P. J.; Keerthisinghe, S.; Linington, R. G.; Britton, R.* "Total Synthesis of Biselide A", Chemical Science, 2021, 12, 5534-5543. doi: 10.1039/D0SC06223E. |
| 86. | Egan, J. M.; van Santen, J. A.; Liu, D. Y.; Linington, R. G.* "Development of an NMR-Based Platform for the Direct Structural Annotation of Complex Natural Products Mixtures", Journal of Natural Products, 2021, 84, 1044-1055. doi: 10.1021/acs.jnatprod.0c01076. |
| 85. | Clark, T. N.; Houriet, J.; Vidar, W. S.; Kellogg, J. J.; Todd, D. A.; Cech, N. B.*; Linington, R. G.* "Interlaboratory Comparison of Untargeted Mass Spectrometry Data Uncovers Underlying Causes for Variability", Journal of Natural Products, 2021, 84, 824-835. doi: 10.1021/acs.jnatprod.0c01376. |
| 84. | van Santen, J. A.; Kautsar, S. A.; Medema, M. H.; Linington, R. G.* "Microbial Natural Product Databases: Moving Forward in the Multi-Omics Era", Natural Product Reports, 2021, 38, 264-278. doi: 10.1039/D0NP00053A. |
2020
| 83. | Kudo, Y.; Awakawa, T.; Du, Y.-L.; Jordan, P. A.; Creamer, K. E.; Jensen, P. R.; Linington, R. G.; Ryan, K. S.; Moore, B. S.* "Expansion of Gamma-Butyrolactone Signaling Molecule Biosynthesis to Phosphotriester Natural Products", ACS Chemical Biology, 2020, 15, 3253 - 3261. doi: 10.1021/acschembio.0c00824. |
| 82. | Claesen, J.; Spagnolo, J. B.; Flores Ramos, S.; Kurita, K. L.; Byrd, A. L.; Aksenov, A. A.; Melnik, A. V.; Wong, W.-R.; Wang, S.; Hernandez, R. D.; Donia, M. S.; Dorrestein, P. C.; Kong, H. H.; Segre, J. A.; Linington, R. G.; Fischbach, M. A.*; Lemon, K. P.* "A Cutibacterium Acnes Antibiotic Modulates Human Skin Microbiota Composition in Hair Follicles", Science Translational Medicine, 2020, 12, eaay5445. doi: 10.1126/scitranslmed.aay5445. |
| 81. | Fergusson, C. H.; Coloma, J. M. F.; Valentine, M. C.; Haeckl, F. P. J.; Linington, R. G.* "Custom Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometric Database for Identification of Environmental Isolates of the Genus Burkholderia and Related Genera", Applied and Environmental Microbiology, 2020, 86, e00354-20. doi: 10.1128/AEM.00354-20. |
| 80. | Kelly, P.; Hadi-Nezhad, F.; Liu, D. Y.; Lawrence, T. J.; Linington, R. G.; Ibba, M.*; Ardell, D. H.* "Targeting tRNA-Synthetase Interactions Towards Novel Therapeutic Discovery Against Eukaryotic Pathogens", PLOS Neglected Tropical Diseases, 2020, 14, e0007983. doi: 10.1371/journal.pntd.0007983. |
| 79. | Yoo, E.; Schulze, C. J.; Stokes, B. H.; Onguka, O.; Yeo, T.; Mok, S.; Gnädig, N. F.; Zhou, Y.; Kurita, K.; Foe, I. T.; Terrell, S. M.; Boucher, M. J.; Cieplak, P.; Kumpornsin, K.; Lee, M. C. S.; Linington, R. G.; Long, J. Z.; Uhlemann, A.-C.; Weerapana, E.; Fidock, D. A.; Bogyo, M.* "The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites", Cell Chemical Biology, 2020, 27, 143-157. doi: 10.1016/j.chembiol.2020.01.001. |
2019
| 78. | van Santen, J. A.; Jacob, G.; Leen Singh, A.; Aniebok, V.; Balunas, M. J.; Bunsko, D.; Carnevale Neto, F.; Castaño-Espriu, L.; Chang, C.; Clark, T. N.; Cleary Little, J. L.; Delgadillo, D. A.; Dorrestein, P. C.; Duncan, K. R.; Egan, J. M.; Galey, M. M.; Haeckl, F. P. J.; Hua, A.; Hughes, A. H.; Iskakova, D.; Khadilkar, A.; Lee, J.-H.; Lee, S.; LeGrow, N.; Liu, D. Y.; Macho, J. M.; McCaughey, C. S.; Medema, M. H.; Neupane, R. P.; O’Donnell, T. J.; Paula, J. S.; Sanchez, L. M.; Shaikh, A. F.; Soldatou, S.; Terlouw, B. R.; Tran, T. A.; Valentine, M.; van der Hooft, J. J. J.; Vo, D. A.; Wang, M.; Wilson, D.; Zink, K. E.; Linington, R. G.* "The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery", ACS Central Science, 2019, 5, 1824-1833. doi: 10.1021/acscentsci.9b00806. |
| 77. | Kautsar, S. A.; Blin, K.; Shaw, S.; Navarro-Muñoz, J. C.; Terlouw, B. R.; van der Hooft, J. J. J.; van Santen, J. A.; Tracanna, V.; Suarez Duran, H. G.; Andreu, V. P.; Selem-Mojica, N.; Alanjary, M.; Robinson, S. L.; Lund, G.; Epstein, S. C.; Sisto, A. C.; Charkoudian, L. K.; Collemare, J.; Linington, R. G.; Weber, T.*; Medema, M. H.* "MIBiG 2.0: a Repository for Biosynthetic Gene Clusters of Known Function", Nucleic Acids Research, 2019, 48, D454-458. doi: 10.1093/nar/gkz882. |
| 76. | Linington, R. G.*; Kubanek, J.; Luesch, H. "New Methods for Isolation and Structure Determination of Natural Products ", Natural Product Reports, 2019, 36, 942-943. doi: 10.1039/C9NP90023C. |
| 75. | Ren, W.; Gries, R.; Kurita, K. L.; McCaughey, C. S.; Alamsetti, S. K.; Linington, R. G.*; Gries, G.*; Britton, R.*."Isolation, Structure Elucidation, and Total Synthesis of Dolichovespulide, a Sesquiterpene from Dolichovespula Yellowjackets.", Journal of Natural Products, 2019, 82, 2009 - 2012. doi: 10.1021/acs.jnatprod.9b00238. |
| 74. | Haeckl, F. P. J.; Baldim, J. L.; Iskakova, D.; Kurita, K. L.; Soares, M. G.; Linington, R. G.*."A selective genome-guided method for environmental Burkholderia isolation.", Journal of Industrial Microbiology and Biotechnology, 2019, 46, 345-362. doi: 10.1007/s10295-018-02121-x. |
| 73. | McAlpine, J.B.; Chen. S.N.; Kutateladze, A.; MacMillan, J.B.; Appendino, G.; Barison, A.; Beniddir, M.A.; Biavatti, M.W.; Bluml, S.; Boufridi, A.; Butler, M.S.; Capon, R.J.; Choi, Y.H.; Coppage, D.; Crews, P.; Crimmins, M.T.; Csete, M.; Dewapriya, P.; Egan, J.M.; Garson, M.J.; Genta-Jouve, G; Gerwick, W.H.; Gross, H. Harper, M.K.; Hermanto, P.; Hook, J.M.; Hunter, L.; Jeannerat, D.; Ji, N.Y.; Johnson, T.A.; Kingston, D.G.I.; Koshino, H.; Lee, H.W.; Lewin, G.; Li, J.; Linington, R.G.; Liu, M.; McPhail, K.L.; Molinski, T.F.; Moore, B.S.; Nam, J.W.; Neupane, R.P.; Niemitz, M.; Nuzillard, J.M.; Oberlies, N.H.; Ocampos, F.M.M.; Pan, G.; Quinn, R.J.; Reddy, D.S.; Renault, J.H.; Rivera-Chávez, J.; Robien, W.; Saunders, C.M.; Schmidt, T.J.; Seger, C.; Shen, B.; Steinbeck, C.; Stuppner, H.; Sturm, S.; Taglialatela-Scafati, O.; Tantillo, D.J.; Verpoorte, R.; Wang, B.G.; Williams, C.M.; Williams, P.G.; Wist, J.; Yue, J.M.; Zhang, C.; Xu, Z.; Simmler, C.; Lankin, D.C.; Bisson, J.; Pauli, G.F.* "The Value of Universally Available Raw NMR data for Transparency, Reproducibility, and Integrity in Natural Product Research..", Natural Product Reports, 2019, 36, 35-107. doi: 10.1039/c7np00064b. |
2018
| 72. | Ueoka, R.; Bhushan, A.; Probst, S.I.; Bray, W.M.; Lokey, R.S.; Linington, R.G.; Piel, J.*."Genome-Based Identification of a Plant-Associated Marine Bacterium as a Rich Natural Product Source.", Angewandte Chemie International Edition, 2018, 57, 14519-14523. doi: 10.1002/anie.201805673. |
| 71. | Corcilius, L.; Liu, D. Y.; Ochoa, J. L.; Linington, R. G.; Payne, R. J.* "Synthesis and Evaluation of Analogues of the Glycinocin Family of Calcium-Dependent Antibiotics.", Organic and Biomolecular Chemistry, 2018, 16, 5310 - 5320. doi: 10.1039/c8ob01268g. |
| 70. | Ren, W.‡; Gries, R.‡; McCaughey, C.‡; Derstine, N.‡; Alamsetti, S. K.; Kurita, K. L.; Tu, L.; Linington, R. G.*; Britton, R.*; Gries, G.* "Maculatic Acids-Sex Attractant Pheromone Components of Bald-Faced Hornets.", Angewandte Chemie International Edition, 2018, 57, 11618 - 11622. doi: 10.1002/anie.201804666. |
| 69. | Giltrap, A. M.; Haeckl, F. P. J.; Kurita, K. L.; Linington, R. G.; Payne, R. J.* "Synthetic Studies Toward the Skyllamycins: Total Synthesis and Generation of Simplified Analogues.", Journal of Organic Chemistry, 2018, 83, 7250-7270. doi: 10.1021/acs.joc.8b00898. |
| 68. | Warner, C. J. A.; Salinas, M.; Zamorano-Sánchez, D.; Bray, W. M.; Lokey, R. S.; Yildiz, F. H.*; Linington, R. G.* "The Bioactive Lipid (S)-Sebastenoic Acid Impacts motility and dispersion in Vibrio cholerae.", Canadian Journal of Chemistry, 2018, 96, 196 - 203. doi: 10.1139/cjc-2017-0334. |
| 67. | Ochoa, J. L.; Sanchez, L. M.; Koo, B.-M.; Doherty, J. S.; Rajendram, M.; Huang, K. C.; Gross, C. A.; Linington, R. G.* "Marine Mammal Microbiota Yields Novel Antibiotic with Potent Activity Against Clostridium difficile.", ACS Infectious Diseases, 2018, 4, 59 - 67. doi: 10.1021/acsinfecdis.7b00105. |
2017
| 66. | Corcilius, L.; Elias, N. T.; Ochoa, J. L.; Linington, R. G.; Payne, R. J.* "Total Synthesis of Glycinocins A - C.", Journal of Organic Chemistry, 2017, 82, 12778 - 12785. doi: 10.1021/acs.joc.7b01959. |
| 65. | Giltrap, A. M.; Haeckl, F. P. J.; Kurita, K. L.; Linington, R. G.; Payne, R. J.* "Total Synthesis of Skyllamycins A - C." Chemistry - A European Journal, 2017, 23, 15046 - 15049. doi: 10.1002/chem.201704277. |
| 64. | Caicedo, J. C.; Cooper, S.; Heigwer, F.; Warchal, S.; Qiu, P.; Molnar, C.; Vasilevich, A. S.; Barry, J. D.; Bansal, H. S.; Kraus, O.; Wawer, M.; Paavolainen, L.; Herrmann, M. D.; Rohban, M.; Hung, J.; Hennig, H.; Concannon, J.; Smith, I.; Clemons, P. A.; Singh, S.; Rees, P.; Horvath, P.; Linington, R. G.; Carpenter, A. E.* "Data-Analysis Strategies for Image-Based Cell Profiling." Nat. Meth. 2017, 14, 849–863. doi: 10.1038/nmeth.4397. |
| 63. | Pye, C.; Bertin, M.; Lokey, R. S.; Gerwick, W. H.*; Linington, R. G.* "Reply to Skinnider and Magarvey: Rates of novel natural product discovery remain high." Proceedings of the National Academy of Sciences, USA, 2017, 114, E6273. doi: 10.1073/pnas.1711139114. |
| 62. | Pye, C.; Bertin, M.; Lokey, R. S.; Gerwick, W. H.*; Linington, R. G.* "Retrospective Analysis of Natural Products Provides Insights for Future Discovery Trends" Proceedings of the National Academy of Sciences, USA, 2017, 114, 5601 - 5606. doi: 10.1073/pnas.1614680114. |
| 61. | Cichewicz, R. H.; Cragg, G. M.; Linington, R. G.; Wright, A. E. "Special Issue in Honor of Professor Phil Crews" Journal of Natural Products, 2017, 80, 579 - 581. doi: 10.1021/acs.jnatprod.7b00161. |
| 60. | Tran, A. T.; Watson, E. E.; Pujari, V.; Conroy, T.; Dowman, L. J.; Giltrap, A. M.; Pang, A.; Wong, W.-R.; Linington, R. G.; Mahapatra, S.; Saunders, J.; Charman, S. A.; West, N. P.; Bugg, T. D. H.; Tod, J.; Dowson, C. G.; Roper, D. I.; Crick, D. C.; Britton, W. J.; Payne, R. J..* "Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis" Nature Communications, 2017, 8, Article number: 14414. doi: 10.1038/ncomms14414. |
| 59. | Morgan, J. M.; Duncan, M. C.; Johnson, K. S.; Diepold, A.; Lam, H.; Dupzyk, A. J.; Martin, L. R.; Wong, W.-R.; Armitage, J. P.; Linington, R. G.; Auerbuch, V.* "Piericidin A1 blocks Yersinia Ysc type III secretion system needle assembly" mSphere, 2017, 2:e00030-17. doi: 10.1128/mSphere.00030-17. |
2016
| 58. | Harms, H.; Kurita, K. L.; Pan, L.; Wahome, P. G.; He, H.; Kinghorn, A. D.; Carter, G. T.; Linington, R. G.* "Discovery of Anabaenopeptin 679 From Freshwater Algal Bloom Material: Insights Into the Structure-Activity Relationship of Anabaenopeptin Protease Inhibitors" Bioorganic and Medicinal Chemistry Letters, 2016, 26, 4960-4965. doi: 10.1016/j.bmcl.2016.09.008. |
| 57. | Wang, M; Carver, J. J.; Phelan, V. V.; Sanchez, L. M.; Garg, N.; Peng, Y.; Nguyen, D. D.; Watrous, J.; Kapono, C. A.; Luzzatto-Knaan, T.; Porto, C.; Bouslimani, A.; Melnik, A. V.; Meehan, M. J.; Liu, W. T.; Crüsemann, M.; Boudreau, P. D.; Esquenazi, E.; Sandoval-Calderón, M.; Kersten, R. D.; Pace, L. A.; Quinn, R. A.; Duncan, K. R.; Hsu, C. C.; Floros, D. J.; Gavilan, R. G.; Kleigrewe, K.; Northen, T.; Dutton, R. J.; Parrot, D.; Carlson, E. E.; Aigle, B.; Michelsen, C. F.; Jelsbak, L.; Sohlenkamp, C.; Pevzner, P.; Edlund, A.; McLean, J.; Piel, J.; Murphy, B. T.; Gerwick, L.; Liaw, C. C.; Yang, Y. L.; Humpf, H. U.; Maansson, M.; Keyzers, R. A.; Sims, A. C.; Johnson, A. R.; Sidebottom, A. M.; Sedio, B. E.; Klitgaard, A.; Larson, C. B.; Boya P, C. A.; Torres-Mendoza, D.; Gonzalez, D. J.; Silva, D. B.; Marques, L. M.; Demarque, D. P.; Pociute, E.; O'Neill, E. C.; Briand, E.; Helfrich, E. J. N.; Granatosky, E. A.; Glukhov, E.; Ryffel, F.; Houson, H.; Mohimani, H.; Kharbush, J. J.; Zeng, Y.; Vorholt, J. A.; Kurita, K. L.; Charusanti, P.; McPhail, K. L.; Nielsen, K. F.; Vuong, L.; Elfeki, M.; Traxler, M. F.; Engene, N.; Koyama, N.; Vining, O. B.; Baric, R.; Silva, R. R.; Mascuch, S. J.; Tomasi, S.; Jenkins, S.; Macherla, V.; Hoffman, T.; Agarwal, V.; Williams, P. G.; Dai, J.; Neupane, R.; Gurr, J.; Rodríguez, A. M. C.; Lamsa, A.; Zhang, C.; Dorrestein, K.; Duggan, B. M.; Almaliti, J.; Allard, P. M.; Phapale, P.; Nothias, L. F.; Alexandrov, T.; Litaudon, M.; Wolfender, J. L.; Kyle, J. E.; Metz, T. O.; Peryea, T.; Nguyen, D. T.; VanLeer, D.; Shinn, P.; Jadhav, A.; Müller, R.; Waters, K. M.; Shi, W.; Liu, X.; Zhang, L.; Knight, R.; Jensen, P. R.; Palsson, B. O.; Pogliano, K.; Linington, R. G.; Gutiérrez, M.; Lopes, N. P.; Gerwick, W. H.; Moore, B. S.; Dorrestein, P. C.; Bandeira, N. "Sharing and Community Curation of Mass Spectrometry Data with Global Natural Products Social Molecular Networking" Nature Biotechnology, 2016, 34, 828-837. doi: 10.1038/nbt.3597. |
| 56. | Giltrap, A. M.; Dowman, L. J.; Nagalingam, G.; Ochoa, J. L.; Linington, R. G.; Britton, W. J.; Payne, R. J.* "Total Synthesis of Teixobactin." Organic Letters, 2016, 18, 2788–2791. doi: 10.1021/acs.orglett.6b01324. |
| 55. | Sanchez, L. M.; Cheng, A. T.; Warner, C. J. A.; Townsley, L.; Peach, K. C.; Navarro, G.; Shikuma, N. J.; Bray, W. M.; Riener, R. M.; Yildiz, F. H.; Linington, R. G.* "Biofilm Formation and Detachment in Gram-Negative Pathogens Is Modulated by Select Bile Acids." PLOS ONE, 2016, 11, e0149603. doi: 10.1371/journal.pone.0149603. |
2015
| 54. | Effenberger, K. A.‡; James, R. C.‡; Urabe, V. K.; Dickey, B. J.; Linington, R. G.*, Jurica, M. S.* "The Natural Product N-palmitoyl-L-leucine Selectively Inhibits Late Assembly of Human Spliceosomes." Journal of Biological Chemistry, 2015, 290, 27524 - 27531. PMID: 26408199. doi: 10.1074/jbc.M115.673210. |
| 53. | Kurita, K. L.; Glassey, E.; Linington, R. G.* "Integration of High-Content Screening and Untargeted Metabolomics for Comprehensive Functional Annotation of Natural Product Libraries." Proceedings of the National Academy of Sciences, USA, 2015, 112, 11999-12004. PMID: 26371303. doi: 10.1073/pnas.1507743112. |
| 52. | Ochoa, J. L.; Bray, W. M.; Lokey, R. S.; Linington, R. G.* "Phenotype-Guided Natural Products Discovery Using Cytological Profiling." Journal of Natural Products, 2015, 78, 2242-2248. PMID: 26292657. doi: 10.1021/acs.jnatprod.5b00455. |
| 51. | Schulze, C. J.; Donia, M. S.; Siqueira-Neto, J. L.; Ray, D.; Raskatov, J. A.; Green, R. E.; McKerrow, J. H.; Fischbach, M. A.; Linington, R. G.* "Genome-Directed Lead Discovery: Biosynthesis, Structure Elucidation, and Biological Evaluation of Two Families of Polyene Macrolactams against Trypanosoma brucei." ACS Chemical Biology, 2015, 16, 2373 - 2381. PMID: 26270237. doi: 10.1021/acschembio.5b00308. |
| 50. | Shao, C. L.; Linington, R. G.; Balunas, M. J.; Centeno, A.; Boudreau, P.; Zhang, C.; Engene, N.; Spadafora, C.; Mutka, T. S.; Kyle, D. E.; Gerwick, L.; Wang, C. Y.; Gerwick, W. H.* “Bastimolide A, a Potent Antimalarial Polyhydroxy Macrolide from the Marine Cyanobacterium Okeania hirsuta.” Journal of Organic Chemistry, 2015, 80, 6849-7855. PMID: 26222145. doi: 10.1021/acs.joc.5b01264. |
| 49. | León, B.; Haeckl, F. J.; Linington, R. G.* “Optimized Quinoline Amino Alcohols as Disruptors and Dispersal Agents of Vibrio cholerae Biofilms.” Organic and Biomolecular Chemistry, 2015, 13, 8495 - 8499. PMID: 26156292. doi: 10.1039/c5ob01134e. |
| 48. | Teschler, J. K.; Zamorano-Sánchez, D.; Utada, A. S.; Warner, C. J. A.; Wong, G. C. L.; Linington, R. G.; Yildiz F. H.* “Living in the Matrix: Assembly and Control of Vibrio cholerae biofilms” Nature Reviews Microbiology, 2015, 13, 255 - 268. PMID: 25895940. doi: 10.1038/nrmicro3433. |
| 47. | Kurita, K. L.; Linington, R. G.* “Connecting Phenotype and Chemotype: High-Content Discovery Strategies for Natural Products Research” Journal of Natural Products, 2015, 78, 587 - 596. PMID: 25728167. doi: 10.1021/acs.jnatprod.5b00017. |
| 46. | Schulze, C. J.‡; Navarro, G.‡; Ebert, D.‡; DeRisi, J.*; Linington, R. G.* “Salinipostins A−K, Long-Chain Bicyclic Phosphotriesters as a Potent and Selective Antimalarial Chemotype” Journal of Organic Chemistry, 2015, 80, 1312-1320. PMID: 25584395. doi: 10.1021/jo5024409. |
| 45. | León, B.‡; Navarro, G.‡; Dickey, B. J.; Stepan, G.; Tsai, A.; Jones, G. S.; Morales, M. E.; Barnes, T.; Ahmadyar, S.; Tsiang, M.; Geleziunas, R.; Cihlar, T.; Pagratis, N.; Tian, Y.; Yu, H.; Linington, R. G.* “Abyssomicin 2 Reactivates Latent HIV‐1 by a PKC- and HDAC- Independent Mechanism” Organic Letters, 2015, 15, 262-265. PMID: 25560385. doi: 10.1021/ol503349y. |
| 44. | Warner, C. J. A; Cheng, A. T.; Yildiz, F. H.; Linington, R. G.* “Development of Benzo[1,4]oxazines as Biofilm Inhibitors and Dispersal Agents Against Vibrio cholerae” ChemComm, 2015, 51, 1305-1308. PMCID: PMC4288701. doi: 10.1039/c4cc07003h. |
2014
| 43. | Schulze, C. J.; Bray, W. M.; Loganzo, F.; Lam, M.-H.; Szal, T.; Villalobos, A.; Koehn, F.; Linington, R. G.* “Borrelidin B: Isolation, Biological Activity, and Implications for Nitrile Biosynthesis” J. Nat. Prod., 2014, 77, 2570-2574. PMID: 25393949. doi: 10.1021/np500727g. |
| 42. | Donia, M.; Cimermancic, P.; Schulze, C. J.; Wieland Brown, L. C.; Martin, J.; Mitreva, M.; Clardy, J.; Linington, R. G.; Fischbach, M. A.* “A Systematic Analysis of Biosynthetic Gene Clusters in the Human Microbiome Reveals a Common Family of Antibiotics” Cell, 2014, 158, 1402-1414. PMCID: PMC4164201. doi: 10.1016/j.cell.2014.08.032. |
| 41. | Cimermancic, P.; Medema, M. H.; Claesen, J.; Kurita, K.; Wieland Brown, L. C.; Mavrommatis, K.; Pati, A.; Godfrey, P. A.; Koehrsen, M.; Clardy, J.; Birren, B. W.; Takano, E.; Sali, A.; Linington, R. G.; Fischbach, M. A.* “Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters” Cell, 2014, 158, 412-421. PMCID: PMC4123684. doi: 10.1016/j.cell.2014.06.034. |
| 40. | Schulze, C. J. and Linington, R. G. (2014) "Image-Based Screening Approaches to Natural Products Discovery." In A. Osbourn, R. Goss & G.T. Carter (Eds.) Natural Products: Discourse, Diversity, and Design (pp. 373-396) New York, NY: Wiley. |
| 39. | Higginbotham, S.*; Wong, W. R.; Linington, R. G.; Spadafora, C.; Iturrado, L.; Arnold, E. A."Sloth Hair as a Novel Source of Fungi with Potent Anti-Parasitic, Anti-Cancer and Anti-Bacterial Bioactivity." PLoS ONE 2014 9(1): e84549. PMCID: PMC3893167. doi: 10.1371/journal.pone.0084549. |
| 38. | Duncan, M. C.; Wong, W. R.; Dupzyk, A. J.; Bray, W. M.; Linington, R. G.; Auerbuch V.* "An NF-κB-Based High Throughput Screen Identifies Piericidins as Inhibitors of the Yersinia pseudotuberculosis Type III Secretion System." Antimicrob. Agents Chemother. 2014, 58, 1118-1126. PMCID: PMC3910828. doi: 10.1128/AAC.02025-13. |
| 37. | Navarro, G.; Cheng, A. T.; Peach, K. C.; Bray, W. M.; Bernan, V. S.; Fitnat H. Yildiz, F. H.; Linington R. G.* "An Image-Based 384-Well High-Throughput Screening Method for the Discovery of Skyllamycins A - C as Biofilm Inhibitors and Inducers of Biofilm Detachment in Pseudomonas aeruginosa" Antimicrob. Agents Chemother. 2014, 58, 1092-1099. PMCID: PMC3910817. doi: 10.1128/AAC.01781-13. |
| 36. | Liu, W.-T.; Lamsa, A.; Wong, W. R.; Boudreau, P. D.; Kersten, R.; Peng, Y.; Moree, W. J.; Duggan, B. M.; Moore, B. S.; Gerwick, W. H.; Linington, R. G.; Pogliano, K.; Dorrestein, P. C. "MS/MS-Based Networking and Peptidogenomics Guided Genome Mining Revealed the Stenothricin Gene Cluster in Streptomyces roseosporus" The Journal of Antibiotics 2014, 67, 99-104. PMCID: PMC3919142. doi: 10.1038/ja.2013.99. |
2013
| 35. | Peach, K. C.; Cheng, A. T.; Oliver, A. G.; Yildiz, F. H.; Linington, R. G.* "Discovery and Biological Characterization of the Auromomycin Chromophore as an Inhibitor of Biofilm Formation in V. cholerae" ChemBioChem 2013, 14, 2209 - 2215. PMCID: PMC3947468. doi: 10.1002/cbic.201300131. |
| 34. | Jane Y. Yang, J. Y.; Sanchez, L. M.; Rath, C. M.; Liu, X.; Boudreau, P. D.; Bruns, N.; Glukhov, E.; Wodtke, A.; De Felicio, R.; Fenner, A.; Wong, W.- R.; Linington, R. G.; Zhang, L.; Debonsi, H. M.; Gerwick, W. H.; Dorrestein P. C.* "Molecular Networking as a Dereplication Strategy" Journal of Natural Products 2013, 76, 1686 - 1699. PMCID: PMC3936340. doi: 10.1021/np400413s. |
| 33. | Peach, K. C.; Bray, W. M.; Winslow, D. Linington, P. F.; Linington, R. G.* "Mechanism of Action-Based Classification of Antibiotics using High-Content Bacterial Image Analysis Molecular Biosystems 2013, 9, 1837 - 1848. PMCID: PMC3674180. doi: 10.1039/c3mb70027e. |
| 32. | León, B.; Fong, J. C. N.; Peach, K. C.; Wong, W.-R.; Yildiz, F. H.; Linington, R. G.* "Development of Quinoline-Based Disruptors of Biofilm Formation Against Vibrio cholerae" Organic Letters 2013, 15, 1234 – 1237. PMID: 23461487. doi: 10.1021/ol400150z. |
| 31. | Sanchez, L. M.; Knudsen, G. M.; Helbig, C.; De Muylder, G.; Mascuch, S. M.; Mackey, Z. B.; Gerwick, L.; Clayton, C.; McKerrow, J. H.; Linington, R. G.* “Examination of the Mode of Action of the Almiramide Family of Natural Products against the Kinetoplastid Parasite Trypanosoma brucei" Journal of Natural Products 2013, 76, 630 – 641. PMCID: PMC3971013. doi: 10.1021/np300834q. |
| 30. | Schulze, C. J.; Bray, W. M.; Woerhman, M. H.; Stuart, J.; Lokey, R. S.; Linington, R. G.* "‘‘Function-First’’ Lead Discovery: Mode of Action Profiling of Natural Product Libraries Using Image- Based Screening" Chemistry and Biology 2013, 20, 285-295. PMCID: PMC3584419. doi: 10.1016/j.chembiol.2012.12.007. |
2012
| 29. | Wong, W.-R.; Oliver, A. G.; Linington, R. G.* "Development of BioMAP Screening for the Classification and Discovery of Natural Product Antibiotics" Chemistry and Biology 2012, 19, 1483-1495. PMID: 23177202. doi: 10.1016/j.chembiol.2012.09.014. |
| 28. | Carlile, G. W.; Keyzers, R. A.; Teske, K. A.; Robert, R.; Williams, D. E.; Linington, R. G.; Gray, C. A.; Centko, R. M.; Yan, L.; Anjos, S. M.; Sampson, H. M.; Zhang, D.; Liao, J.; Hanrahan, J. W.; Andersen, R. J.; Thomas, D. Y.* "Correction of F508del-CFTR trafficking by the sponge alkaloid latonduine is modulated by interaction with PARP" Chemistry and Biology 2012, 19, 1288-1299. PMID: 23102222. doi: 10.1016/j.chembiol.2012.08.014. |
| 27. | Navarro, G.; Chokpaiboon, S.; De Muylder, G.; Bray, W. M.; Nisam, S. C.; McKerrow, J. H.; Pudhom, K.; Linington, R. G.*, "Hit-to-Lead Development of the Chamigrane Endoperoxide Merulin A for the Treatment of African Sleeping Sickness" PLoS ONE 2012, 9, e46172. PMCID: PMC3459870. doi: 10.1371/journal.pone.0046172. |
| 26. | Duncan, M. C.; Linington, R. G.; Auerbuch, V.* "Chemical inhibitors of the type three secretion system: disarming bacterial pathogens" Antimicrobial Agents and Chemotherapy, 2012, 56, 5433-5441. PMCID: PMC3486574. doi: 10.1128/AAC.00975-12. |
| 25. | Sanchez, L. M.; Wong, W. R.; Riener, R. M.; Schulze, C. J.; Linington, R. G.* “Examining the Fish Microbiome: Vertebrate-Derived Bacteria as an Environmental Niche for the Discovery of Unique Marine Natural Products” PLoS ONE 2012, 7, e35398. PMCID: PMC3344833. doi: 10.1371/journal.pone.0035398. |
2011
| 24. | White, T. R; Renzelman, C. M.; Rand, A. C.; Rezai, T.; Mcewen, C. M.; Gelev, V. M.; Turner, R. A.; Linington, R. G.; Leung, S. S. F.; Kalgutkar, A. S.; Bauman, J. N.; Zhang, Y.; Liras, S.; Price, D. A.; Mathiowetz, A. M.; Jacobson, M. P.*; Lokey, R. S.* "On-resin n-methylation of cyclic peptides for discovery of orally bioavailable scaffolds" Nat. Chem. Bio. 2011, 7, 810 - 817. PMCID: PMC3210067. doi: 10.1038/nchembio.664. |
| 23. | Conroy, T.; Guo, J. T.; Linington, R. G.; Hunt, N. H.; Payne, R. J.* "Total Synthesis, Stereochemical Assignment, and Antimalarial Activity of Gallinamide A" Chem. Eur. J. 2011, 17, 13544-13552. PMID: 22006835. doi: 10.1002/chem.201102538. |
| 22. | Radjasa, O.K.; Vaske, Y.M.; Navarro, G.; Vervoort, H.C.; Tenney, K.; Linington, R.G.; Crews, P.* "Highlights of marine invertebrate-derived biosynthetic products: their biomedical potential and possible production by microbial associants." Bioorg. Med. Chem. 2011, 19, 6658-6674. PMCID: PMC3205244. doi: 10.1016/j.bmc.2011.07.017. |
| 21. | Nunnery, J. K.; Suyamaa, T. L.; Linington, R. G.; Gerwick, W. H.* "Expedient synthesis of α,α-dimethyl-β-hydroxy carbonyl scaffolds via Evans’ aldol reaction with a tertiary enolate" Tet. Lett. 2011, 52, 2929-2932. PMCID: PMC3100194. doi: 10.1016/j.tetlet.2011.03.126. |
| 20. | Sanchez, L. M.; Curtis, M. E.; Bracamonte, B. E.; Kurita, K. L.; Navarro, G.; Sparkman, O. D.; Linington, R. G.* "Versatile method for the detection of covalently bound substrates on solid supports by DART mass spectrometry" Org. Lett. 2011, 13, 3770-3773. PMCID: PMC3146587. doi: 10.1021/ol201404v. |
| 19. | Peach, K. C.; Bray, W. M.; Shikuma, N. J.; Gassner, N. C.; Lokey, R. S.; Yildiz, F. H.; Linington, R. G.* "An image-based 384-well high-throughput screening method for the discovery of biofilm inhibitors in Vibrio cholerae" Mol. Biosyst. 2011 1176 – 1184. PMID: 21246108. doi: 10.1039/c0mb00276c. |
2010
| 18. | Liu, X.; Beyhan, S.; Lim, B.; Linington, R. G.; Yildiz, F. H.* "Identification and characterization of a phosphodiesterase that inversely regulates motility and biofilm formation in Vibrio cholerae" J Bacteriol. 2010, 192, 4541-4552. PMCID: PMC2937418. doi: 10.1128/JB.00209-10. |
| 17. | Sanchez, L. M.; Lopez, D.; Vesely, B. A.; Della Togna, G.; Gerwick, W. H.; Kyle, D. E.; Linington, R. G.* “Almiramides A-C: Discovery and Development of a New Class of Leishmaniasis Lead Compounds” J. Med. Chem., 2010, 53, 4187 - 4197. PMCID: PMC4418807. doi: 10.1021/jm100265s. |
| 16. | Balunas, M. J.; Linington, R. G.; Tidgewell, K.; Fenner, A. M.; Urena, L.-D.; Della Togna, G.; Kyle, D. E.; Gerwick, W. H.* “Dragonamide E, a Modified Linear Lipopeptide from Lyngbya majuscula with Antileishmanial Activity” J. Nat. Prod., 2010, 73, 60 - 66. PMCID: PMC2834186. doi: 10.1021/np900622m. |
2009
| 15. | Peach, K. C.; Linington, R. G.* “New Innovations for an Old Infection: Antimalarial Lead Discovery from Marine Natural Products during the Period 2003–2008” Future Medicinal Chemistry, 2009, 1, 593 – 617. doi: 10.4155/fmc.09.56. |
| 14. | Ng, J.; Bandeira, N.; Liu, W.-T.; Ghassemian, M.; Simmons, T. L.; Gerwick, W. H.; Linington, R. G.; Dorrestein, P. C.; Pevzner, P. A.* “Dereplication and De Novo Sequencing of Nonribosomal Peptides” Nat. Methods, 2009, 6, 596 – 599. PMCID: PMC2754211. doi: 10.1038/nmeth.1350. |
| 13. | Liu, W.-T.; Ng, J.; Meluzzi, D.; Bandeira, N.; Gutierrez, M.; Simmons, T. L.; Schultz, A. W.; Linington, R. G.; Moore, B. S.; Gerwick, W. H.; Pevzner, P. A.; Dorrestein, P. C.* "Interpretation of Tandem Mass Spectra Obtained from Cyclic Nonribosomal Peptides." Anal. Chem. 2009, 81, 4002 - 4009. PMCID: PMC2765223. doi: 10.1021/ac900114t. |
| 12. | Linington, R. G.; Clark, B. R.; Trimble, E. E.; Almanza, A.; Ureña, L. D.; Kyle, D. E.; Gerwick, W. H.* "Antimalarial Peptides from Marine Cyanobacteria: Isolation and Structural Elucidation of Gallinamide A" J. Nat. Prod., 2009, 72, 14 - 17. PMCID: PMC2760338. doi: 10.1021/np8003529. |
2008 and earlier
| 11. | Linington, R. G.; Edwards, D. J.; Shuman, C. F.; McPhail, K. L.; Matainaho, T.; Gerwick, W. H.* “Symplocamide A, a Potent Cytotoxin and Chymotrypsin Inhibitor from the Marine Cyanobacterium Symploca sp.” J. Nat. Prod., 2008, 71, 22-27. PMCID: PMC2832912. doi: 10.1021/np070280x. |
| 10. | Bandeira, N.; Ng, J.; Meluzzi, D.; Linington, R. G.; Dorrestein, P.; Pevzner, P. A.* "De Novo Sequencing of Nonribosomal Peptides." Research in Computational Molecular Biology; Proceedings of the Twelfth Annual International Conference on Computational Molecular Biology (RECOMB 2008), 181 - 195. |
| 9. | McPhail, K. L.; Correa, J.; Linington, R. G.; Gonzalez, J.; Ortega-Barria, E.; Capson, T. L.; Gerwick, W. H.* “Antimalarial Linear Lipopeptides from a Panamanian Strain of the Marine Cyanobacterium Lyngbya majuscula.” J. Nat. Prod., 2007, 70, 984-988. PMCID: PMC2745555. doi: 10.1021/np0700772. |
| 8. | Linington, R. G.; Gonzalez, J.; Ureña, L. D.; Romero, L.; Ortega-Barría, E.; Gerwick, W. H.* “Venturamides A and B: Antimalarial Constituents of the Panamanian Marine Cyanobacterium Oscillatoria sp.” J. Nat. Prod., 2007, 70, 397 – 401. PMID: 17328572. doi: 10.1021/np0605790. |
| 7. | Kursar, T. A.; Caballero-George, C. C.; Capson, T. L.; Cubilla-Ríos, L.; Gerwick, W. H.; Heller, M. V.; Ibañez, A.; Linington, R. G.; McPhail, K. L.; Ortega-Barría, E.; Romero, L. I.; Coley, P. D. “Linking Bioprospecting with Sustainable Development and Conservation: the Panama Case” Biodiversity and Conservation, 2007, 16, 2789-2800. doi: 10.1007/s10531-007-9214-2. |
| 6. | Linington, R. G.; Robertson, M.; Gauthier, A.; Finlay, B. B.; MacMiIlan, J.; Molinski, T. F.; van Soest, R.; Andersen, R. J.* “Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia” J. Nat. Prod. 2006, 69, 173 - 177 .PMID: 16499312. doi: 10.1021/np050192h. |
| 5. | Kursar, T. A.; Caballero, C. C.; Capson T. L.; Cubilla-Rios, L.; Gerwick, W. H.; Ibañez, A.; Linington, R. G.; McPhail, K. L.; Ortega-Barría, E.; Romero, L.; Coley, P. “Securing Economic Benefits and Promoting Conservation through Bioprospecting” BioScience 2006, 56, 1005 -1012. doi: 10.1641/0006-3568(2006)56[1005:SEBAPC]2.0.CO;2. |
| 4. | MacMillan, J.; Linington, R. G.; Andersen, R.; Molinski, T. F.* “Stereochemical assignment in acyclic lipids across long distance by circular dichroism: Absolute stereochemistry of the aglycone of caminoside A” Angewandte Chemie 2004, 43, 5946-5951. PMID: 15547902. doi: 10.1002/anie.200461158. |
| 3. | Linington, R. G.; Williams, D. E.; Tahir, A.; van Soest, R.; Andersen, R.* “Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri: Structure elucidation, synthesis, and biogenetic implications” Org. Lett. 2003, 5, 2735 – 2738.PMID: 12868902. doi: 10.1021/ol034950b. |
| 2. | Linington, R. G.; Robertson, M.; Gauthier, A.; Finlay, B. B.; van Soest, R.; Andersen, R. J.* “Caminoside A, an antimicrobial glycolipid isolated from the marine sponge Caminus sphaeroconia” Org. Lett. 2002, 4, 4089 – 4092. PMID: 12423093. doi: 10.1021/ol0268337. |
| 1. | Barsby, T.; Linington, R. G.; Andersen, R.* “De novo terpenoid biosynthesis by the dendronotid nudibranch Melibe leonina” Chemoecology, 2002, 12, 199 – 202. doi: 10.1007/PL00012669. |
‡Authors contributed equally.